Research Abstract

In my laboratory, we focus on two major areas of research: (1) studying the neural mechanisms of detecting and recognizing pheromones, and (2) developing new optical methods for imaging neuronal activity.

In the mouse, pheromones are detected primarily by the neurons of the vomeronasal organ, which project their axons to a distinct brain region called the accessory olfactory bulb... read more


Selected Publications

  • Turaga D. and Holy T.E. (2012) Organization of vomeronasal sensory coding revealed by fast volumetric calcium imaging. J. Neurosci. 32: 1612-1621.
  • Meeks JP, Arnson HA, and Holy TE. Representation and transformation of chemosensory information in the mouse accessory olfactory system. Nature Neuroscience. 2010 13: 723-730.
  • Turaga D and Holy TE. Image-based calibration of a deformable mirror in wide-field microscopy. Applied Optics. 2010 49: 2030-2040.
  • Nodari F, Hsu F-F, Fu X, Holekamp TF, Kao L-F, Turk J, Holy TE. Sulfated steroids as natural ligands of mouse pheromone-sensing neurons. J. Neuroscience. 2008 28: 6407-6418.
  • Holekamp TF, Turaga D, Holy TE. Fast three-dimensional fluorescence imaging of activity in neural populations by objective-coupled planar illumination microscopy. Neuron. 2008 57: 661-672.

For a complete list of Dr. Holy's publications, click here.

Timothy Holy, PhD

Associate Professor of Neuroscience

Washington University
School of Medicine
Campus Box 8108
North Building, 4401
St. Louis, MO 63110
(314) 362-0086
holy@wustl.edu

Other Information

Education
1991 BA, Mathematics and Physics (summa cum laude), Rice University

1992 MA, Physics, Princeton University

1997 PhD, Physics, Princeton University, Thesis advisor: Stanislas Leibler


Selected Honors
2005, 2008, 2014 Distinguished Teaching Service Award

2007 McKnight Technological Innovation in Neuroscience Award

2009 St. Louis Academy of Sciences Innovation Award

2009 NIH Director's Pioneer Award

2009 Society for Neuroscience Research Award for Innovation in Neuroscience (RAIN)