Publications

Clemens AW, Gabel HW, Emerging insights into the distinctive neuronal methylome. Trends in Genetics, in press. 2020. 

Christian DL*, Wu DY*, Martin JR, Moore JR, Liu YR, Clemens AW, Nettles SA, Kirkland NM, Hill CA, Wozniak DF, Dougherty JD, Gabel HW, DNMT3A haploinsufficiency results in behavioral deficits and global epigenomic dysregulation shared across neurodevelopment disorders. 13 July 2020. doi: https://doi.org/10.1101/2020.07.10.195859

Goodman JV, Yamada T, Yang Y, Kong L, Wu DY, Zhao G, Gabel HW, Bonni A, The chromatin remodeling enzyme Chd4 regulates genome architecture in the mouse brain. Nature Communications. 9 July 2020. https://doi.org/10.1038/s41467-020-17065-z

Kopp ND, Nygaard KR, Liu Y, McCullough KB, Maloney SE, Gabel HW, Dougherty JD, Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA binding and long-term behavioral consequences. Human Molecular Genetics. 1 May 2020. https://doi.org/10.1093/hmg/ddaa070

Clemens AW*, Wu DY*, Moore JR, Christian DL, Zhao G, Gabel HW, MeCP2 Represses Enhancers through Chromosome Topology-Associated DNA Methylation Mol Cell. 2019 Nov 26. doi: 10.1016/j.molcel.2019.10.033

Kinde BZ, Wu DY, Greenberg ME, Gabel HW DNA methylation in the gene body influences MeCP2-mediated gene repression PNAS. 2016 Dec 13. pii: 201618737. [Epub ahead of print]

Gabel HW*, Kinde BZ*, Stroud H, Harmin DA, Hemberg M, Gilbert CS, Ebert DH, Greenberg ME Disruption of DNA-methylation-dependent long gene repression in Rett syndrome. Nature. 2015 Jun 4;522(7554):89-93. doi: 10.1038/nature14319. Epub 2015 Mar 11.

Kinde BZ*, Gabel HW*, Gilbert CS, Griffith EC, Greenberg M.E. Reading the unique DNA methylation landscape of the brain: Non-CpG methylation, hydroxymethylation, and MeCP2. PNAS. 2015 Jun 2;112(22):6800-6. doi: 10.1073/pnas.1411269112. Epub 2015 Mar 4.

Spiegel* I, Mardinly* AR, Gabel HW, Bazinet JE, Couch CH, Tzeng CP, Harmin DA, & Greenberg ME Npas4 regulates excitatory-inhibitory balance within neural circuits through cell type-specific gene programs. Cell. 2014 May 22;157(5):1216-29. doi: 10.1016/j.cell.2014.03.058.

Ebert DH, Gabel HW, Robinson ND, Kastan NR, Hu LS, Navarro AJ, Lyst MJ, Ekiert R, Bird AP, and Greenberg ME. Activity-Dependent Phosphorylation of MeCP2 T308 Regulates Interaction with NCoR Nature. 2013 Jul 18;499(7458):341-5. doi: 10.1038/nature12348

Cohen S*, Gabel HW*, Hemberg M, Hutchinson AN, Sadacca LA, Ebert DH, Harmin DA, Greenberg RS, Verdine VK, Zhou Z, Wetsel WC, West AE, Greenberg ME. Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function. Neuron. 2011 Oct 6;72(1):72-85.

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