Department of Neuroscience

Research Abstract

In my laboratory, we focus on two major areas of research: (1) studying the neural mechanisms of detecting and recognizing pheromones, and (2) developing new optical methods for imaging neuronal activity.

In the mouse, pheromones are detected primarily by the neurons of the vomeronasal organ, which project their axons to a distinct brain region called the accessory olfactory bulb... read more

Selected Publications

• Turaga D. and Holy T.E. (2012) Organization of vomeronasal sensory coding revealed by fast volumetric calcium imaging. J. Neurosci. 32: 1612-1621.
• Meeks JP, Arnson HA, and Holy TE. Representation and transformation of chemosensory information in the mouse accessory olfactory system. Nature Neuroscience. 2010 13: 723-730.
• Turaga D and Holy TE. Image-based calibration of a deformable mirror in wide-field microscopy. Applied Optics. 2010 49: 2030-2040.
• Nodari F, Hsu F-F, Fu X, Holekamp TF, Kao L-F, Turk J, Holy TE. Sulfated steroids as natural ligands of mouse pheromone-sensing neurons. J. Neuroscience. 2008 28: 6407-6418.
• Holekamp TF, Turaga D, Holy TE. Fast three-dimensional fluorescence imaging of activity in neural populations by objective-coupled planar illumination microscopy. Neuron. 2008 57: 661-672.

For a complete list of Dr. Holy's publications, click here.